Figure 3
From: Metallothionein-3 promotes cisplatin chemoresistance remodelling in neuroblastoma
Evaluation of efficiency of CDDP to inhibit tumour growth and metastatic spread in UKF-NB-4mock cells and their hMT3 counterparts. (A) Weights of tumours excised from the CAM upon experiment termination (17th day). Numbers of Nbl cells identified in (B) distal CAM (extravasation), (C) liver, (D) lung and (E) brain (intravasation). Quantitation of Nbl cells was based on qPCR using Alu primers. In addition, qPCR of chicken GAPDH was performed as an internal control to confirm the presence of equivalent quantities of host genomic DNA. Data shows average ± SEM from three (n = 3) independent experiments. *p < 0.05; **p < 0.005, ***p < 0.001, ****p < 0.0001.
