Figure 13

Albumin expression of HepG2 clusters formed in shell compartment in co-culture with NIH 3T3 embedded in core compartment (upper panel) and in monoculture (cell-free core; lower panel). In both, co-culture and monoculture, the core was composed of algMC, algMC + fibrin and algMC + plasma. Confocal images of HepG2 stained for Albumin (purple), nuclei (blue) and cytoskeletons (green); scale bars represent 50 µm.