Figure 1

Characterization of exosomes derived from HCs and SUDs peripheral blood. (A) Representative nanoparticle tracking analysis report of exosomes from study participants. (B) Representative transmission electron micrograph images of exosomes derived from study participants, scale bar = 200 nm. (C) Western blot analysis showing the presence of three common positive exosomal markers (CD63, TSG101 and ALIX) and one negative exosomal marker (Calnexin) in exosomes isolated from study participants. PC positive control, Exp Experimental group.