Scientific Reports

Table 2 Correlation of coagulation proteins with (A) Body mass index (BMI), (B) inflammation (C reactive protein; CRP) and (C) insulin resistance (HOMA-IR), (D) shows the results of the multivariate analysis taking into account BMI, CRP and HOMA-IR.

From: Metabolic consequences of obesity on the hypercoagulable state of polycystic ovary syndrome

A. BMI			B. CRP			C. HOMA-IR			D. CRP + BMI + HOMA-IR
	p value	r²		p value	r²		p value	r²		p value	r²
Antithrombin.III	< 0.00001	0.154	Antithrombin III	< 0.00001	0.202	Antithrombin III	< 0.00001	0.140	D.dimer	0.06	0.151
Fibrinogen gamma chain	0.00004	0.101	Heparin cofactor.2	0.00002	0.116	Heparin cofactor 2	0.0007	0.070	Fibrinogen gamma chain	0.07	0.179
Vitamin.K dependent protein S	0.0007	0.070	Fibrinogen gamma chain	0.00003	0.111	P.selectin	0.001	0.066	Fibrinogen	0.07	0.089
D.dimer	0.0008	0.068	D.dimer	0.00012	0.094	Fibronectin	0.009	0.042	Plasma kallikrein	0.09	0.051
Fibronectin	0.0008	0.068	P.selectin	0.0012	0.067	Vitamin.K dependent protein.S	0.015	0.037	Fibronectin Fragment.4	0.12	0.064
Prothrombin	0.007	0.044	Fibronectin	0.0014	0.066	Alpha.2 antiplasmin	0.02	0.032	Vitamin.K dependent protein.S	0.14	0.089
Heparin cofactor.2	0.009	0.042	Fibronectin Fragment.3	0.006	0.050	Prothrombin	0.05	0.024	von Willebrand factor	0.14	0.035
Fibrinogen	0.013	0.038	Fibronectin Fragment.4	0.007	0.047	Fibronectin Fragment.3	0.09	0.018	Coagulation factor.Xa	0.19	0.030
Angiostatin	0.014	0.037	Vitamin K dependent protein.S	0.02	0.037	Plasma kallikrein	0.18	0.011	Antithrombin.III	0.19	0.264
Fibronectin Fragment.3	0.03	0.031	Alpha.2 antiplasmin	0.02	0.036	Tissue Factor	0.20	0.010	Fibronectin	0.24	0.094
P.selectin	0.04	0.026	Fibrinogen	0.02	0.035	Fibrinogen gamma chain	0.24	0.009	Fibronectin Fragment.3	0.31	0.060
Alpha.2 antiplasmin	0.16	0.012	von Willebrand factor	0.12	0.016	Fibronectin Fragment.4	0.32	0.006	Tissue Factor	0.40	0.030
Fibronectin Fragment.4	0.18	0.011	Plasma kallikrein	0.18	0.012	D.dimer	0.43	0.004	Angiostatin	0.41	0.056
Tissue.Factor	0.19	0.011	Prothrombin	0.19	0.011	Angiostatin	0.50	0.003	Prothrombin	0.42	0.048
von.Willebrand factor	0.26	0.008	Coagulation factor.Xa	0.22	0.010	Coagulation Factor.XI	0.81	0.000	Alpha.2 antiplasmin	0.42	0.052
Coagulation factor Xa	0.49	0.003	Tissue.Factor	0.71	0.001	Coagulation factor.Xa	0.83	0.000	Heparin cofactor 2	0.58	0.133
Coagulation Factor.XI	0.66	0.001	Coagulation Factor.XI	0.73	0.001	von Willebrand factor	0.87	0.000	Coagulation Factor.XI	0.70	0.005
Plasma kallikrein	0.97	0.000	Angiostatin	0.74	0.001	Fibrinogen	0.93	0.000	P.selectin	0.71	0.096

Bolded numbers indicate significant differences between PCOS and control groups, at the p < 0.05 level.

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