Figure 4 | Scientific Reports

Figure 4

From: PHACTR1 genetic variability is not critical in small vessel ischemic disease patients and PcomA recruitment in C57BL/6J mice

Figure 4

Copy number variant plot (CNV) plot across Phactr1 locus based on genome sequencing data from BCCAS mice with different vascular phenotypes: three BCCAS mice with two very prominent PcomAs and ECA retrograde flow, which did not develop any ischemic lesion detectable on T2-weighted MRI both 1 and 7 days post-surgery (Fig. 2BI) and 3 BCCAS mice with no PcomAs and ECA retrograde flow,which developed severe hemispheric lesions and died within a few hours-one day post-surgery (Fig. 2BII).

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