Table 1 List of genes whose expression levels of miRNAs were significantly more than three times higher in MCs from OA patients than in MCs from RA patients.

Systematic_name	Fold increase ([RA] vs [OA])	Regulation ([RA] vs [OA])	[OA] (raw)	[RA] (raw)	[OA] (normalized)	[RA] (normalized)
ebv-miR-BART12	− 69.01	Down	5.22	0.10	− 1.64	− 7.74
hsa-miR-4254	− 5.50	Down	1.87	0.10	− 5.28	− 7.74
hsa-miR-564	− 5.34	Down	1.71	0.10	− 5.33	− 7.74
hsv2-miR-H22	− 5.27	Down	1.65	0.10	− 5.35	− 7.74
hsa-miR-193b	− 4.41	Down	0.99	0.10	− 5.60	− 7.74
hsa-miR-498	− 4.35	Down	0.96	0.10	− 5.62	− 7.74
hsa-miR-718	− 4.24	Down	0.89	0.10	− 5.66	− 7.74
hsa-miR-4327	− 4.21	Down	8.03	8.61	− 1.00	− 3.08
hsa-miR-127-3p	− 4.18	Down	0.86	0.10	− 5.68	− 7.74
hsa-miR-342-5p	− 4.14	Down	0.83	0.10	− 5.69	− 7.74
hsa-miR-3149	− 4.12	Down	0.82	0.10	− 5.70	− 7.74
hsv1-miR-H8	− 4.04	Down	0.78	0.10	− 5.73	− 7.74
hsa-miR-3117	− 3.95	Down	5.35	5.02	− 1.62	− 3.61
hsa-miR-199a-3p	− 3.67	Down	18.34	30.16	− 0.27	− 2.14
hsa-miR-34a*	− 3.44	Down	1.65	1.52	− 4.15	− 5.93
hsv1-miR-H6-5p	− 3.34	Down	2.43	2.31	− 2.61	− 4.35
hsa-miR-664*	− 3.28	Down	2.96	3.79	− 2.39	− 4.10
hsa-miR-502-3p	− 3.25	Down	3.87	4.80	− 1.94	− 3.64
hcmv-miR-US4	− 3.23	Down	0.43	0.10	− 6.05	− 7.74
hsa-miR-1288	− 3.20	Down	4.03	4.72	− 2.00	− 3.68

Raw data from miRNA microarrays, normalized normalized data obtained from miRNA microarrays (please see “Materials and methods” section), MCs mast cells, OA osteoarthritis, RA rheumatoid arthritis.

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