Table 2 Faecal carriage rate of CTXM, plasmid-mediated AmpC, and plasmid-mediated quinolone resistance alleles in 61 healthy people.

From: High fecal carriage of blaCTX-M, blaCMY-2, and plasmid-mediated quinolone resistance genes among healthy Korean people in a metagenomic analysis

Antibiotic resistance alleles

% (number)

P for trend

Total

HARG

MARG

LARG

CTX-M

23% (14)

60% (6)

17.1% (7)

10% (1)

0.008

CTX-M-1G

11.5% (7)

30% (3)

7.3% (3)

10% (1)

0.164

CTX-M-9G

16.4% (10)

50% (5)

12.2% (5)

0% (0)

0.003

Plasmid-mediatedAmpC

16.4% (10)

40% (4)

12.2% (5)

10% (1)

0.072

 CMY-1

0% (0)

0% (0)

0% (0)

0% (0)

 

 CMY-2

13.1% (8)

20% (2)

12.2% (5)

10% (1)

0.511

 FOX

0% (0)

0% (0)

0% (0)

0% (0)

 

 DHA

3.3% (2)

20% (2)

0% (0)

0% (0)

0.013

Plasmid-mediatedquinolone resistance

59% (36)

60% (6)

65.9% (27)

30% (3)

0.176

 qnrA

0% (0)

0% (0)

0% (0)

0% (0)

 

 qnrB

44.3% (27)

60% (6)

43.9% (18)

30% (3)

0.18

 qnrD

4.9% (3)

10% (1)

4.9% (2)

0% (0)

0.213

 qnrS

54.1% (33)

50% (5)

61% (25)

30% (3)

0.373

 qepA

0% (0)

0% (0)

0% (0)

0% (0)

 

 aac(6′)-Ib-cr

13.1% (8)

10% (2)

12.2% (5)

10% (1)

0.511

Total (median, [1Q, 3Q])

 

2 (0.8, 4.3)

1 (0, 2)

0 (0, 0.8)

0.035*

  1. Plasmid-mediated carbapenemase alleles were not identified.
  2. HARG high antibiotic resistance genes group, MARG middle antibiotic resistance genes group, LARG low antibiotic resistance genes group.
  3. CTX-M-1G, CTX-M-1 group; CTX-M-9G, CTX-M-9 group.
  4. *By Kruskal‒Wallis test.