Table 2 Correlation between serum CA15-3, CEA and SF in canine mammary gland tumor and clinicopathological parameters.

From: Combined detection of CA15-3, CEA, and SF in serum and tissue of canine mammary gland tumor patients

Clinicopathological parameters

Number (%)

CA15-3 (U/mL)

CEA (ng/mL)

SF (ng/mL)

Age*

 ≤ 10 years

33 (58.8%)

9.757 ± 5.832

28.52 ± 19.07

609.9 ± 236.5

 > 10 years

23 (41.2%)

10.06 ± 5.850

26.20 ± 18.51

497.4 ± 217.3

P-value

 

0.335

0.203

0.863

Tumor location*

Multiple

24 (42.4%)

10.11 ± 6.079

25.67 ± 18.08

549.5 ± 247.8

Single

32 (57.6%)

8.711 ± 4.651

28.99 ± 19.33

574.3 ± 224.9

P-value

 

0.067

0.445

0.201

Tumor mass size#

T1 (< 3 cm)

12 (21.4%)

11.23 ± 6.506

28.29 ± 18.53

611.2 ± 224.8

T2 (3–5 cm)

28 (50.0%)

10.18 ± 5.779

26.21 ± 17.82

580.5 ± 244.8

T3 (> 5 cm)

16 (28.6%)

8.359 ± 5.044

29.39 ± 20.66

498.7 ± 211.4

P-value

 

 > 0.05

 > 0.05

 > 0.05

Lymph node involvement*

    

N0

41 (73.2%)

8.235 ± 5.364

21.88 ± 16.41

498.7 ± 227.3

N1

15 (26.8%)

14.39 ± 4.588

43.09 ± 16.27

738.8 ± 159.8

P-value

 

 < 0.01

 < 0.01

 < 0.01

Metastasis*

M0

44 (78.6%)

8.312 ± 4.747

22.83 ± 17.64

508.8 ± 222.8

M1

12 (21.4%)

15.64 ± 4.902

44.94 ± 11.76

765.1 ± 157.7

P-value

 

 < 0.01

 < 0.01

 < 0.01

Histologic grade#

I

21 (37.5%)

7.659 ± 4.705

20.72 ± 15.21

497.3 ± 199.9

II

25 (44.6%)

9.173 ± 5.114

27.09 ± 20.26

535.4 ± 238.3

III

10 (17.9%)

16.33 ± 5.103

43.14 ± 11.94

773.9 ± 169.9

P-value

 

 < 0.05

 < 0.05

 < 0.05

  1. *Unpaired t test; #one ANOVA test; P < 0.05 show significant difference; P < 0.01 show extremely significant difference.