Table 4 Sensitivity, specificity, accuracy, and Youden index of single and combined detections of serum CA15-3, CEA and SF levels in canine mammary gland tumors.

From: Combined detection of CA15-3, CEA, and SF in serum and tissue of canine mammary gland tumor patients

Tumor markers

Sensitivity (%)

Specificity (%)

Accuracy (%)

Youden index (%)

CA15-3

51.8 (29/56)

93.9 (77/82)

76.8 (106/138)

0.457

CEA

44.6 (25/56)

84.1 (69/82)

68.1 (94/138)

0.287

SF

62.5 (35/56)

85.4 (70/82)

76.1 (105/138)

0.479

CA15-3 + CEA

64.2 (36/56)

81.7 (67/82)

74.6 (103/138)

0.459

CA15-3 + SF

71.4 (40/56)

84.1 (69/82)

78.9 (109/138)

0.555

CEA + SF

66.1 (37/56)

79.2 (65/82)

73.9 (102/138)

0.453

CA15-3 + CEA + SF

80.4 (45/56)

78.0 (64/82)

80.0 (109/138)

0.584