Table 4 Area Under the Curve measurements for all biomarkers and combinations thereof.

From: Validation and verification of predictive salivary biomarkers for oral health

Biomarkers or combinations thereof

Health versus gingivitis

Health versus periodontitis

Gingivitis versus periodontitis

MMP-8

0.73

0.92

0.74

MMP-9

0.78

0.95

0.79

TIMP-1

0.67

0.85

0.76

Ratio: MMP-8/TIMP-1

0.78

0.97

0.87

Ratio: MMP-9/TIMP-1

0.80

0.98

0.89

Sum: MMP-8 + MMP-9

0.76

0.95

0.89

Ratio: (MMP-8 + MMP-9)/TIMP-1

0.81

0.98

0.89

LBP

0.75

0.87

0.68

MMP-2

0.74

0.96

0.82

MMP-3

0.84

0.86

0.54

OPG

0.54

0.86

0.82

IL-1b

0.71

0.89

0.80

IL-8

0.55

0.57

0.64

HGF

0.75

0.97

0.87

  1. The values above the thresholds are represented with bold numbers.