Table 3 Performance comparisons between the HS-RTP, the N-RTP, and culture under different conditions, including overall specimens, pulmonary specimens (sputum, bronchoalveolar lavage (BAL) and bronchial washing (BW)), extrapulmonary specimens, AFS-positive specimens and AFS-negative specimens. AFS: acid fast stain; + : positive; − : negative. N: sample size.

From: Development of a two-step nucleic acid amplification test for accurate diagnosis of the Mycobacterium tuberculosis complex

 

Culture + 

Culture − 

All specimens (N = 134)

HS-RTP + 

77

11

HS-RTP − 

2

44

N-RTP + 

75

6

N-RTP − 

4

49

Pulmonary specimens (N = 73)

HS-RTP + 

52

5

HS-RTP − 

2

14

N-RTP + 

52

2

N-RTP − 

2

17

Extra-pulmonary specimens (N = 61)

HS-RTP + 

25

6

HS-RTP − 

0

30

N-RTP + 

23

4

N-RTP − 

2

32

On AFS positive specimens (N = 51)

HS-RTP + 

45

5

HS-RTP − 

1

0

N-RTP + 

45

2

N-RTP − 

1

3

On AFS negative specimens (N = 83)

HS-RTP + 

32

6

HS-RTP − 

1

44

N-RTP + 

30

4

N-RTP − 

3

46