Figure 1 | Scientific Reports

Figure 1

From: Focused ultrasound mediated blood–brain barrier opening is safe and feasible in a murine pontine glioma model

Figure 1

Tumor implantation and experimental setup (a) Skull coordinates for intra-pontine tumor implantation. Injections were made 1 mm lateral and 1 mm caudal to the lambda, and 6 mm deep to the skull. (b) On H&E, the tumor exhibited hypercellularity and mitotic figures consistent with high-grade glioma. (c) Tumor growth was confirmed on contrast-enhanced T1-weighted MR imaging. (d) Experimental setup for FUS-mediated BBB opening.

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