Table 2 Univariate and multivariate cox proportional hazards regression analysis for recurrence free survival.

From: Genome-wide identification and characterization of circular RNA in resected hepatocellular carcinoma and background liver tissue

Variables

Univariate analysis

Multivariate analysis

HR

95% CI

p

HR

95% CI

p

Age (years)

≥ 65 vs < 65

1.061

0.793–1.420

0.689

1.156

0.814–1.643

0.418

Sex

Male vs female

1.439

0.935–2.215

0.098

1.475

0.861–2.528

0.157

AFP (ng/mL)

≥ 20 vs < 20

1.337

0.997–1.793

0.052

1.240

0.869–1.769

0.236

Child–Pugh classification

B vs A

1.249

0.834–1.869

0.281

1.296

0.775–2.166

0.323

Stage

III/IV vs I/II

1.481

1.099–1.996

0.010

1.128

0.783–1.626

0.517

hsa_circ_0001020 expression in HCC

Low vs high

1.502

1.106–2.041

0.009

1.276

0.872–1.868

0.209

hsa_circ_0036683 expression in HCC

Low vs high

2.020

1.363–2.993

 < 0.001

1.661

1.046–2.637

0.031

hsa_circ_0058087 expression in HCC

Low vs high

1.819

1.174–2.818

0.007

1.706

1.063–2.736

0.027

  1. HR hazard ratio, CI confidence interval, AFP alpha-fetoprotein.
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