Table 3 Univariate and multivariate cox proportional hazards regression analysis for overall survival.

From: Genome-wide identification and characterization of circular RNA in resected hepatocellular carcinoma and background liver tissue

Variables

Univariate analysis

Multivariate analysis

HR

95% CI

p

HR

95% CI

p

Age, years

≥ 65 vs < 65

1.183

0.843–1.660

0.330

1.180

0.785–1.772

0.426

Sex

Male vs female

1.164

0.715–1.892

0.542

1.161

0.635–2.123

0.628

AFP, ng/mL

 ≥ 20 vs < 20

1.582

1.121–2.231

0.009

1.616

1.064–2.453

0.024

Child–Pugh classification

B vs A

1.420

0.912–2.209

0.121

1.504

0.849–2.662

0.162

Stage

III/IV vs I/II

1.516

1.074–2.139

0.018

1.274

0.841–1.930

0.253

hsa_circ_0001020 expression in HCC

Low vs high

1.540

1.073–2.211

0.019

1.314

0.834–2.070

0.238

hsa_circ_0036683 expression in HCC

Low vs high

1.837

1.179–2.862

0.007

1.708

1.006–2.900

0.048

hsa_circ_0058087 expression in HCC

Low vs high

1.645

1.015–2.666

0.043

1.442

0.851–2.444

0.174

  1. HR hazard ratio, CI confidence interval, AFP alpha-fetoprotein.
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