Table 2 Clinical characteristics of NSCLC patients on the basis of the fifteen-mRNA signature in the training (n = 226, GSE31210) internal validation (n = 226, GSE30219) and external validation (n = 181, GSE50081) sets.

From: A highly expressed mRNA signature for predicting survival in patients with stage I/II non-small-cell lung cancer after operation

Characteristics

Training Set(n = 226, GSE31210)

Internal Validation Set(n = 226, GSE30219)

External Validation Set (n = 181, GSE50081)

High-risk (n = 113)

Low-risk (n = 113)

P-value

High-risk (n = 113)

Low-risk (n = 113)

P-value

High-risk (n = 90)

Low-risk (n = 91)

P-value

Age (years)

 < 60

51

45

0.5

38

50

0.133

12

15

0.677

 ≥ 60

62

68

 

75

63

 

78

76

 

Gender

Male

61

44

0.03

104

88

0.005

41

41

1

Female

52

69

 

9

25

 

49

49

 

Stage

I

61

107

 < 0.01

71

90

 < 0.01

64

63

1

II

52

6

 

42

23

 

26

27

 
  1. The clinical characteristics of the external independent variables (age, sex, stage) between the low-risk group and the high-risk group were not significantly different.