Table 1 OrientGene point-of-care SARS-CoV-2 serology testing (n = 200) among inpatients, March–April 2020, London.

From: Point-of-care SARS-CoV-2 serological assays for enhanced case finding in a UK inpatient population

SARS-CoV-2 PCR

Days post symptom onset

OrientGene serology results

CXM

CGX

CGM

CXX

(a)

Positive

5–9

4

3

30

13

10–14

1

2

40

7

 > 14

1

0

49

0

Negative

N/A

2

0

0

48

8

5

119

68

 

SARS-CoV-2 PCR positive

SARS-CoV-2 PCR negative

   

(b)

   

OrientGene test positive

130

2

OrientGene test negative

20

48

Whole cohort sensitivity = 87%; negative rate = 96% (n = 200)

Days post-symptom onset

n

Sub-group sensitivity (%)

   

(c)

   

5–9

50

74

10–14

50

86

 > 14

50

100

  1. (a) Control, IgM, and IgG line detection across different symptom durations, where C control line only, G IgM line observed, M IgM line observed.
  2. (b) Sensitivity and negative rate across all 200 assays.
  3. (c) Sensitivity and negative rate across different symptom durations.
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