Table 1 Baseline characteristics of patients.
1996–2007 (n = 505) | 2008–2019 (n = 355) | Total (n = 860) | p | ||||
---|---|---|---|---|---|---|---|
n | % or range | n | % | n | % | ||
Gender | 0.487 | ||||||
Male | 275 | 54.46 | 202 | 56.9 | 477 | 55.47 | |
Female | 230 | 45.54 | 153 | 43.1 | 383 | 44.53 | |
Age | 0.173 | ||||||
Median, range | 8.56 | 0–18 | 10.64 | 0–18 | 9.48 | 0–18 | |
WBC (k/ml) | 0.016 | ||||||
Median, range | 27.36 | 0.7–726 | 21.58 | 0.5–639.4 | 23.6 | 0.5–726 | |
FAB | 0.008 | ||||||
M0 | 26 | 5.15 | 14 | 3.94 | 40 | 4.65 | |
M1 | 65 | 12.87 | 43 | 12.11 | 108 | 12.56 | |
M2 | 151 | 29.9 | 112 | 31.55 | 263 | 30.58 | |
M4 | 80 | 15.84 | 62 | 17.46 | 142 | 16.51 | |
M5 | 62 | 12.28 | 53 | 14.93 | 115 | 13.37 | |
M6 | 18 | 3.56 | 8 | 2.25 | 26 | 3.02 | |
M7 | 54 | 10.69 | 39 | 10.99 | 93 | 10.81 | |
M8 | 0 | 0 | 1 | 0.28 | 1 | 0.12 | |
M9 | 20 | 3.96 | 21 | 5.92 | 41 | 4.77 | |
Unknown | 29 | 5.74 | 2 | 0.56 | 31 | 3.6 | |
Chromosome | < 0.0001 | ||||||
-5/del(5q)/-7/del(7q) | 11 | 2.18 | 8 | 2.25 | 19 | 2.21 | |
11q23 | 14 | 2.77 | 12 | 3.38 | 26 | 3.02 | |
Complex | 34 | 6.73 | 32 | 9.01 | 66 | 7.67 | |
N/A | 127 | 25.15 | 26 | 7.32 | 153 | 17.79 | |
Normal | 130 | 25.74 | 91 | 25.63 | 221 | 25.7 | |
Other | 83 | 16.44 | 76 | 21.41 | 159 | 18.49 | |
inv(16) | 17 | 3.37 | 20 | 5.63 | 37 | 4.3 | |
t(6;9) | 4 | 0.79 | 0 | 0 | 4 | 0.47 | |
t(8;21) | 74 | 14.65 | 69 | 19.44 | 143 | 16.63 | |
t(9;11) | 8 | 1.58 | 20 | 5.63 | 28 | 3.26 | |
t(9;22) | 3 | 0.59 | 1 | 0.28 | 4 | 0.47 |