Table 1 Summary of literature reference, gene pairs pre- (Stage 1) and post- (Stage 2) curation used for building the key event (KE) networks.

From: Application of text mining to develop AOP-based mucus hypersecretion genesets and confirmation with in vitro and clinical samples

 

Primary document corpus

Curated corpus

Number of seed genes

Number of abstract retrieved

Total number of unique genes from retrieved abstracts

Number of abstracts after curation

Total number of unique genes after curation

Unique genes in detail

List of gene pairs

KE1

1

718

215

165 + 12a

25

S-genes: 1; R-genes: 18; A-genes: 6

See Table S12

KE2

21

17,570

1242

244 + 6a

KE2: 35; KE2-KE3: 124

S-genes: 20 (one duplicate removed); R-genes: 8; A-genes: 7

See Table S13

KE3

84

42,465

1873

265 + 6a

KE3: 106; KE2-KE3: 124

S-genes: 84; R-genes: 16; A-genes: 6

See Table S14

KE4

34

2115

516

80 + 11a

50

S-genes: 34; R-genes: 13; A-genes: 3

See Table S15

KE5

44

192

114

7 + 13a

51

S-genes: 42 (one duplicate and one false acronym removed); R-genes: 0; A-genes: 9

See Table S16

  1. aIndicates number of genes that were added after a further manual inspection of key references.