Table 1 Dose indices of organs-at-risk.

From: Effects of deep inspiration breath hold on prone photon or proton irradiation of breast and regional lymph nodes

Dose (Gy /GyRBE)

Photon

Proton

Ph/Pr DIBH

Ph/Pr SB

DIBH

SB

p-value

DIBH

SB

p-value

p-value

p-value

Heart (mean)

2.54

(1.43–4.31)

4.55

(2.40–6.58)

 < 0.001

0.78

(0.10–2.11)

1.34

(0.53–2.50)

 < 0.001

 < 0.001

 < 0.001

Heart apex (mean)

4.15

(1.24–14.05)

11.07

(1.51–26.33)

 < 0.001

3.44

(0.04–9.56)

4.35

(0.02–12.00)

0.17

0.05

 < 0.001

LAD (mean)

6.50

(2.04–17.56)

11.09

(3.02–23.16)

 < 0.001

2.19

(0.02–7.56)

2.26

(0.02–14.64)

0.90

 < 0.001

 < 0.001

Lung left (mean)

4.72

(3.38–6.85)

5.44

(3.93–7.43)

 < 0.001

3.70

(2.26–5.57)

3.05

(1.74–4.68)

 < 0.001

 < 0.001

 < 0.001

Lung right (mean)

0.93

(0.26–2.90)

1.04

(0.23–3.36)

0.17

0.14

(0.03–0.46)

0.08

(0.03–0.36)

0.002

 < 0.001

 < 0.001

Lungs (mean)

2.71

(1.72–4.45)

3.08

(2.04–4.89)

 < 0.001

1.78

(1.05–2.80)

1.44

(0.79–2.34)

 < 0.001

 < 0.001

 < 0.001

Esophagus (mean)

2.97

(1.09–6.35)

3.38

(1.16–6.91)

0.02

2.99

(0.24–6.95)

3.27

(0.06–7.43)

0.14

0.90

0.66

Esophagus (D02)

20.67

(5.17–39.23)

21.23

(2.97–40.35)

0.67

25.45

(3.44–40.98)

25.20

(0.54–40.51)

0.81

0.001

0.02

Thyroid (mean)

5.08

(1.43–16.37)

5.22

(0.78–11.90)

0.77

8.52

(0.77–18.48)

8.49

(0.58–20.26)

0.96

 < 0.001

 < 0.001

Brachial Plexus (D02)

43.83

(40.16–49.85)

42.85

(37.36–(47.82)

0.01

41.16

(40.12–42.16)

41.05

(38.32–42.33)

0.40

 < 0.001

 < 0.001

Spinal cord (D02)

4.15

(1.06–16.60)

4.38

(0.99–18.89)

0.69

0.19

(0.04–2.67)

0.076152

(0.04–0.60)

0.19

 < 0.001

 < 0.001

Spinal cord (isotropic expansion 5 mm (D02)

5.50

(1.13–18.10)

5.90

(1.24–25.31)

0.53

0.29

(0.04–3.01)

0.141765

(0.04–0.88)

0.11

 < 0.001

 < 0.001

Contralateral breast (mean)

1.15

(0.25–2.57)

1.18

(0.46–1.88)

0.59

0.11

(0.02–0.25)

0.09

(0.02–0.25)

0.04

 < 0.001

 < 0.001

  1. Average values (range) for 31 patients. P-values for paired t-test. Column 6: p-values for photon DIBH versus photon SB plans. Column 11: p-values for proton DIBH versus proton SB plans. Column 12: p-values for DIBH photon versus DIBH proton plans. Column 13: p-values for SB photon versus SB proton plans.
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