Table 1 Maternal and clinical characteristics of women with preterm prelabor rupture of membranes based on the presence and absence of intra-amniotic infection.
Characteristic | The presence of intra-amniotic infection (n = 19) | The absence of intra-amniotic infection (n = 151) | p-value |
|---|---|---|---|
Maternal age [years, median (IQR)] | 30 (24–33) | 31 (27–35) | 0.19 |
Primiparous [number (%)] | 10 (53%) | 90 (60%) | 0.63 |
Pre-pregnancy body mass index [kg/m2, median (IQR)] | 22.8 (20.9–25.2) | 24.0 (21.2–27.2) | 0.25 |
Smoking [number (%)] | 3 (16%) | 25 (17%) | 1.00 |
Interval between PPROM and amniocentesis [hours, median (IQR)] | 3 (2–8) | 4 (2–7) | 0.57 |
Gestational age at admission [weeks, median (IQR)] | 29 + 3 (27 + 0–33 + 4) | 34 + 3 (32 + 3–35 + 3) | 0.0003 |
Gestational age at delivery [weeks, median (IQR)] | 29 + 6 (27 + 3–33 + 4) | 34 + 5 (33 + 0–35 + 6) | < 0.0001 |
Latency between PPROM and delivery [hours, median (IQR)] | 60 (17–113) | 45 (13–157) | 0.70 |
Amniotic fluid IL-6 levels at admission [pg/nL, median (IQR)] | 30,932 (9427–50,000) | 667 (329–50,000) | < 0.0001 |
CRP levels at admission [mg/L, median (IQR)] | 19.2 (3.3–36.5) | 5.2 (2.5–8.2) | 0.003 |
WBC count at admission [×109 L, median (IQR)] | 14.9 (11.2–17.6) | 11.9 (9.9–14.3) | 0.03 |
Administration of corticosteroids [number (%)] | 15 (79%) | 89 (59%) | 0.13 |
Vaginal delivery [number (%)] | 13 (68%) | 108 (72%) | 0.79 |
Birth weight [grams, median (IQR)] | 1460 (1090–2220) | 2290 (1930–3620) | < 0.0001 |
Apgar score < 7; 5 min [number (%)] | 3 (16%) | 5 (3%) | 0.05 |
Apgar score < 7; 10 min [number (%)] | 2 (11%) | 2 (1%) | 0.06 |
