Table 2 Maternal and clinical characteristics of women with spontaneous preterm labor with intact membranes based on the presence and absence of intra-amniotic infection.
Characteristic | The presence of intra-amniotic infection (n = 12) | The absence of intra-amniotic infection (n = 67) | p-value |
|---|---|---|---|
Maternal age [years, median (IQR)] | 27 (25–28) | 28 (23–30) | 0.86 |
Primiparous [number (%)] | 7 (58%) | 47 (70%) | 0.50 |
Pre-pregnancy body mass index [kg/m2, median (IQR)] | 27.5 (23.1–30.6) | 25.0 (23.0–27.9) | 0.51 |
Smoking [number (%)] | 1 (8%) | 7 (10%) | 1.00 |
Gestational age at admission [weeks, median (IQR)] | 27 + 6 (26 + 6–31 + 2) | 30 + 6 (26 + 6–32 + 3) | 0.17 |
Gestational age at delivery [weeks, median (IQR)] | 29 + 0 (27 + 1–33 + 3) | 32 + 6 (29 + 0–36 + 5) | 0.04 |
Interval from amniocentesis to delivery [days, median (IQR)] | 2 (0–15) | 5 (1–39) | 0.10 |
Amniotic fluid IL-6 levels at admission [pg/mL, median (IQR)] | 43,431 (23,597–50,000) | 1495 (484–4050) | < 0.0001 |
CRP levels at admission [mg/L, median (IQR)] | 42.0 (7.5–75.1) | 6.0 (2.4–11.4) | 0.0007 |
WBC count at admission [×109 L, median (IQR)] | 16.3 (14.1–19.5) | 13.9 (10.6–16.5) | 0.05 |
Administration of corticosteroids [number (%)] | 9 (75%) | 57 (85%) | 0.41 |
Vaginal delivery [number (%)] | 9 (75%) | 55 (82%) | 0.69 |
Birth weight of the newborn [grams, median (IQR)] | 1230 (936–1958) | 1940 (130–2690) | 0.03 |
Apgar score < 7; 5 min [number (%)] | 3 (25%) | 7 (10%) | 0.17 |
Apgar score < 7; 10 min [number (%)] | 2 (17%) | 3 (5%) | 0.16 |
