Figure 1 | Scientific Reports

Figure 1

From: The TOMM40 ‘523’ polymorphism in disease risk and age of symptom onset in two independent cohorts of Parkinson’s disease

Figure 1

Age of onset of PD symptom curves for TOMM40 ‘523’ genotypes. (A–C) indicate the age at which symptoms of PD began when stratified by TOMM40 ‘523’ genotype, as demonstrated by Kaplan–Meier curves. (C–E) indicate the age at which symptoms of PD began when stratified by TOMM40 ‘523’ and APOE genotype, as demonstrated by Kaplan–Meier curves. PPMI, Parkinson’s Progression Markers Initiative; S/S, short/short; S/L, short/long; S/VL, short/very long; L/L, long/long; L/VL, long/very long; VL/VL, very long/very long; S, short; L, long; VL, very long; ε2/ε2, Apolipoprotein epsilon 2/epsilon 2; ε2/ε3, Apolipoprotein epsilon 2/epsilon 3; ε2/ε4, Apolipoprotein epsilon 2/epsilon 4; ε3/ε3, Apolipoprotein epsilon 3/epsilon 3; ε3/ε4, Apolipoprotein epsilon 3/epsilon 4; ε4/ε4, Apolipoprotein epsilon 4/epsilon 4.

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