Table 1 Top 10 genes of most important nodes within Major Depressive Disorder (MDD) data. Ranking was derived via the nodes betweenness of centrality.
Gene symbol | Location | MDD | BP | References | ||
|---|---|---|---|---|---|---|
1 | FHL1 | Four and a half LIM domains 1 | chrX:136,146,702-136,211,359 | No | ||
2 | NCK2 | NCK adaptor protein 2 | chr2:105,744,912-105,894,274 | No | ||
3 | MTOR | Mechanistic target of Rapamycin kinase | chr1:11,106,531-11,262,557 | Yes | ||
4 | CEP170 | Centrosomal protein 170 | chr1:243,124,428-243,255,406 | No | ||
5 | PRKCZ | Protein kinase C zeta | chr1:2,050,411-2,185,395 | No | Yes | |
6 | EIF3M | Eukaryotic translation initiation factor 3 subunit M | chr11:32,583,767-32,606,2 | Yes | ||
7 | EIF6 | Eukaryotic translation initiation factor 6 | chr20:35,278,906-35,284,985 | No | ||
8 | VPS35 | Vacuolar protein sorting-associated protein 35 | chr16:46,656,132-46,689,518 | Yes | ||
9 | SAP130 | Spliceosome-associated protein 130 | chr2:127,941,217-128,028,120 | Maybe | ||
10 | KLHDC4 | Kelch domain containing 4 | chr16:87,696,485-87,765,997 | Yes |
