Table 2 Plasmodium antigen immunoassay results.

From: Analysis of false-negative rapid diagnostic tests for symptomatic malaria in the Democratic Republic of the Congo

 

Overall

RDT-negative

RDT-positive

p

Tested, n

97

23

74

 

HRP2-positive, n (%)

96 (99.0)

22 (95.7)

74 (100.0)

0.24

HRP2, MFI-background geom. mean (geom. SD)

10,276 (2.9)

11,751 (1.7)

6,675 (7)

0.90

pLDH-positive, n (%)

72 (74.2)

15 (65.2)

57 (77.0)

0.28

pLDH, MFI-background geom. mean (geom. SD)

408 (8.4)

440 (9)

319 (6.5)

0.52

pAldolase-positive, n (%)

92 (94.8)

21 (91.3)

71 (95.9)

0.56

pAldolase, MFI-background geom. mean (geom. SD)

1419 (5.5)

1571 (5.4)

1022 (5.9)

0.46

  1. Frequencies and log-transformed mean values were compared using the Fisher’s exact test and Kruskal–Wallis rank sum test, respectively. MFI-background values are visualized in Fig. 5.
  2. RDT rapid diagnostic test, MFI-background mean fluorescence intensity minus background, SD standard deviation.
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