Figure 2 | Scientific Reports

Figure 2

From: Third generation cephalosporins and piperacillin/tazobactam have distinct impacts on the microbiota of critically ill patients

Figure 2

Family level taxonomic composition of the (A) endotracheal, (B) perineal and (C) faecal microbiota samples collected within and after 48 h of antibiotic administration (for 3GC and TZP groups) or admission to the ICU (control group). 3GC-third-generation cephalosporins, TZP-piperacillin/tazobactam, control-no β-lactams. OTUs that were not assigned to a family are categorised as “Family unassigned”. Bacterial families with a relative abundance less than 3% in all three treatments for each body site are grouped as “Other”. Family level taxonomic abundance for each patient is shown in Supplementary Fig. S3 with details on the sample size per treatment group provided in Supplementary Table S1. The relative abundance of the 16S rRNA gene amplicons in the families were determined using QIIME and graphed using GraphPad Prism (version 9, GraphPad Software, USA, www.graphpad.com).

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