Table 4 Univariate and multiple Cox regression overall survival analyses for CD8 of TILs percentages in ovarian tissues.

From: PD-1 and PD-L1 expression on TILs in peritoneal metastases compared to ovarian tumor tissues and its associations with clinical outcome

 

Overall survival

 

Univariate

Multiple

 

HR [CI95%]

P-value

HR [CI95%]

P-value

CD8 TILs

(≥ 43.3% vs. < 43.3%)

0.64 [0.37–1.09]

0.098

0.52 [0.29–0.91]

0.023

Age (decades)

1.64 [1.33–2.02]

 < 0.001

1.86 [1.41–2.46]

 < 0.001

Histology (HGSOC > Other)

4.11 [2.00–8.45]

 < 0.001

3.97 [1.72–9.19]

0.001

Figo (IV > III > II > I)

2.55 [1.70–3.83]

 < 0.001

1.84 [1.23–2.76]

0.003

Residual tumor mass (R1 > R0)

2.91 [159–5.31]

 < 0.001

2.24 [1.21–4.17]

0.011

  1. Combined hazard ratios and p-values for the dichotomized CD8 expression of TILs in univariate Cox-regressions (left) or multiple Cox-regressions, corrected for age, FIGO stage, and residual tumor mass (right). HR, Hazard Ratio; 95%CI, 95% Confidence Interval; OS, overall survival.
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