Figure 6
From: Morphofunctional analysis of human pancreatic cancer cell lines in 2- and 3-dimensional cultures

A hypothetical model of the characteristics of PDAC cell lines in 2D and 3D culture. Most PDAC cells show pleomorphic morphology under 2D culture and display epithelial-to-mesenchymal features. In the 3D culture, the PDAC cells form spheres of different shapes with various cellular behaviors.