Table 1 Backgrounds of the study patients.

From: Pretreatment PSA levels affects the completion rate of Ra-223 treatment

 

Complete arm

Incomplete arm

Number of activities (mean)

5–6 (5.9)

1–4 (2.9)

Cases

30

10

Age (mean)

54–90 (70.5) years

59–86 (71.1) years

PS

0

28

7

1

2

2

2

0

1

Use of bone modifying agents

Yes

18

8

No

12

2

Previous abiraterone or enzalutamide

Yes

21

8

No

9

2

Previous chemotherapy (docetaxel or cabazitaxel)

Yes

13

8

No

17

2

PSA before Ra-223 treatment (ng/ml) [median]

0.01–860.25 [5.88]

22.49–2259.18 [113.15]

< 10

17

0

≥ 10, < 100

9

5

≥ 100, < 1000

2

4

≥ 1000

2

1

ALP before Ra-223 treatment (U/L) [median]

135–1499 [245]

136–535 [228]

BAP before Ra-223 treatment (ng/L) [median]

6.4–141 [12.9]

8.5–49.9 [13.1]

Extent of bone disease

2–5 metastases

14

3

6–20 metastases

7

0

 > 20 metastases

9

7

Superscan

0

0

  1. PS: performance status; PSA: prostate specific antigen; ALP: alkaline phosphatase; BAP: bone-specific ALP.