Figure 4
From: CT based radiomic approach on first line pembrolizumab in lung cancer
Picture shows two explanatory cases of pretreatment contrast enhanced CT at portal-venous phase and the associated Texture analysis extracted with a dedicated software (TexRAD version 3.2.0, Feedback Medical Ltd,Cambridge, UK; https://fbkmed.com/texrad-landing-2/). (A) shows a patient with good prognosis with an Overall Survival (OS) of 24 months and partial response to treatment while (E) represents a patient with poor prognosis, an OS of 3 months and a progression free survival (PFS) of two months concluded with death; Texture analysis at different spatial scale filters (SSF) is shown for fine SFF in (B,F), medium in (C,G) and coarse in (D,I). In line with the cut-off of 56.22 found on the Kaplan–Meier analysis, above which patients show good OS and PFS: patient reported in (A), with excellent OS had an MPP value at SSF 2 of 74.76 while patient depicted in (E) with poor OS had an MPP value at SFF 2 of 38,97.
