Figure 5
From: Structure based analysis of KATP channel with a DEND syndrome mutation in murine skeletal muscle
Effects of R50P mutation to skeletal muscle myogenesis. (a,b) Kir6.2/WT and Kir6.2/R50P expression in a C2C12 myotube cultured for 96 h after AAV vector infection coding (a) Kir6.2/WT (b) Kir6.2/R50P. Representative images are shown. Scale bar 20 μm. (c,d) R50P mutation does not affect the myogenic index as described in the text. Data are the mean ± SEM per treatment group, each examining 20 randomly selected fields. Mean myotube widths (c) and distribution of myotube widths (d) were calculated for each treatment group. The figures were created by GraphPad Prism software (GraphPad Prism 8.2.1).
