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Figure 1

From: Comparative in silico genome analysis of Clostridium perfringens unravels stable phylogroups with different genome characteristics and pathogenic potential

Figure 1

Whole-genome alignment of Clostridium perfringens strains. (A) A representative detail of the multiple genome alignment depicting genomic conservation within the strains in respect to the physical location of Locally Collinear Blocks (LCBs) and relative order of the genes. Please see Figure S1 for a detailed alignment of the 34 genomes. (B) Alignment of the C. perfringens genomes showing inversions and shifts (NCTC 11144, NCTC 8081 and NCTC 8359) relative to the reference strain (ATCC 13124). In strain NCTC 11144, a large inversion bordered by rRNA operons was observed while the inversions and shifts in the strains NCTC 8081 and NCTC 8359 were bordered by the IS element ISCpe7. Position 1 in all strains corresponds to the origin of replication as determined in strain 13. The alignment was generated using progressiveMauve 73 and edited in Adobe Photoshop CS5 (www.adobe.com/photoshop).

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