Figure 5 | Scientific Reports

Figure 5

From: Comparative in silico genome analysis of Clostridium perfringens unravels stable phylogroups with different genome characteristics and pathogenic potential

Figure 5

Association between core-genome SNPs and accessory gene content of 206 Clostridium perfringens genomes. (A) A maximum-likelihood phylogenetic tree based on core genome SNPs as presented in Fig. 3A with phylogroups being highlighted, shown as a coloured band next to the ML phylogeny. The phylogenetic tree was visualized using iTOL81 (B) A heat map showing the distribution of the 4,099 accessory genes (genes shared by 2—95% of the genomes). Rows represent the accessory genes present in each genome while columns represent accessory gene families. Black and light grey colourations specify accessory gene presence and absence, respectively. Accessory genes were clustered as indicated by the dendrogram (top) using clustering functions from the ComplexHeatmap R package. Genes specifically present or absent in different groups are highlighted (bottom). Heat maps were generated in R using the package ComplexHeatmap 87,91. The figure was edited in Adobe Photoshop CS5 (www.adobe.com/photoshop).

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