Figure 6

Distribution of virulence-related genes and putative iron uptake systems in the 206 Clostridium perfringens genomes. The presence and absence of genes are presented next to the maximum likelihood phylogeny with the origin of isolates being depicted, similar to Fig. 3A. Coloured cells denote the gene presence and white denotes gene absence. The dotted horizontal line refers to the virulence profile of the Darmbrand strain. The locus tag NCTC8081_02938 describes the toxin gene homolog found in the Darmbrand strain. The iron uptake systems are numbered as follow: feoAB operon for ferrous iron-acquisition systems (numbered 1 to 3), two putative heme acquisition systems (4 and 5), one putative ferric citrate iron acquisition system (6) and three putative siderophore iron acquisition systems (7 to 9). The column headers for the iron uptake systems are locus tags of genes from strain 13 [1 and 4 to 9] and ATCC 13124 [2 and 3]. The figure was produced using iTOL ⁸¹.