Table 1 Clinicopathological characteristics of patients with pancreatic cancer that underwent neoadjuvant therapy, showing the coincidence or discrepancy between macroscopy and histology.
From: Adequate tissue sampling for the assessment of pathological tumor regression in pancreatic cancer
| Ā | Total | Coincidence | Discrepancy | |||
|---|---|---|---|---|---|---|
Number of patients, n (%) | 137 | 101 (74) | 36 (26) | |||
Age, y | ||||||
Mean, range | 69, 49ā87 | 70, 49ā87 | 66, 49ā84 | |||
āā„ā70, n (%) | 64 (47) | 53 (39) | 11 (8) | |||
Sex, male, n (%) | 86 (63) | 67 (49) | 19 (14) | |||
Preoperative treatment, n (%) | ||||||
CRT | 85 | 68 (79) | 17 (21*) | |||
CT | 52 | 33 (65) | 19 (35) | |||
Vascular invasion, n (%) | ||||||
Positive | 18 | 14 (78) | 4 (22) | |||
Negative | 119 | 87 (73) | 32 (27) | |||
Perineural invasion, n (%) | ||||||
Positive | 109 | 82 (75) | 27 (25) | |||
Negative | 28 | 19 (68) | 9 (32) | |||
Resection margin negative, n (%) | 119 (87) | 90 (66) | 29 (21) | |||
Stage (UICC 8th), n (%) | ||||||
0 | 2 | 2 (100) | 0 (0) | |||
IA | 7 | 4 (57) | 3 (43) | |||
IB | 12 | 9 (75) | 3 (25) | |||
IIA | 48 | 37 (77) | 11 (23) | |||
IIB | 51 | 35 (69) | 16 (31) | |||
III | 14 | 13 (93) | 1 (7) | |||
IV | 3 | 1 (33) | 2 (67) | |||
Cancer size, meanā±āS.D., mm | 30.0ā±ā15.9 | 28.9ā±ā15.9 | 32.9ā±ā15.9 | |||
Cancer location, n (%) | ||||||
Head | 93 | 66 (71) | 27 (29) | |||
Body/Tail | 44 | 35 (80) | 9 (20) | |||
Pathological differentiation, n (%) | ||||||
Well | 70 | 52 (74) | 18 (26) | |||
Moderately | 50 | 35 (70) | 15 (30) | |||
Poorly | 12 | 9 (75) | 3 (25) | |||
Unclassified | 5 | 5 (100) | 0 (0) | |||
Evans, n (%) | ||||||
I, IIa | 131 | 98 (75) | 33 (25) | |||
IIb, III, IV | 6 | 3 (50) | 3 (50) | |||
JPS, n (%) | ||||||
1 | 126 | 95 (75) | 31 (25) | |||
2ā4 | 11 | 6 (55) | 5 (45) | |||
CAP, n (%) | ||||||
0ā2 | 15 | 14 (93) | 1 (7*) | |||
3 | 122 | 87 (71) | 35 (29) | |||
ART, n (%) | ||||||
0ā3 | 55 | 43 (78) | 12 (22) | |||
4 | 82 | 58 (71) | 24 (29) | |||
Necrosis, n (%) | ||||||
Low, ~ā19% | 70 | 58 (83) | 12 (17*) | |||
High, 20%ā~ | 67 | 43 (64) | 24 (36) | |||
T/S ratio, n (%) | ||||||
Low, ~ā39% | 95 | 71 (75) | 24 (25) | |||
High, 40%ā~ | 42 | 30 (71) | 12 (29) | |||