Figure 5
From: Identifying the major lactate transporter of Toxoplasma gondii tachyzoites
TgFNT1 is critical for l-lactate transport across the parasite plasma membrane. (a,c,e) Time courses for the uptake of l-lactate (a), 2-DOG (c) and L-arginine (e) by wild-type parasites (blue symbols), Δtgfnt1 parasites (white symbols) and Δtgfnt1/2/3 parasites (dark red symbols). The data shown are the mean ± SD from three to four independent experiments for each line. For clarity, only positive or negative error bars are shown for the data for certain parasite lines. Where not shown, error bars fall within the symbols. (b,d,f) The initial rates of uptake for l-lactate (b), 2-DOG (d), and L-arginine (f) estimated from the same set of experiments. The bars show the mean ± SD obtained from three or four independent experiments for each line, and the symbols show the results obtained in individual experiments. For panels b,d and f, the data for each parasite line were compared with the data for every other parasite line (one-way ANOVA, followed by post hoc Tukey tests where significant differences were present). ***P < 0.001; other comparisons (those in d and f) did not reveal significant differences.
