Figure 3
From: Osteoinductive 3D printed scaffold healed 5 cm segmental bone defects in the ovine metatarsus

Histomorphometry evaluations of bone, scaffold, and soft tissue area fraction were performed within the ROI (bounded by blue). Example ROIs are shown for (A) the scaffold treatment group, in which the ROI is bounded by the scaffold perimeter, and (B) the control treatment group, in which the ROI is bounded by the new bone growth in the 5 cm defect region. Additionally, for the scaffold treatments, the area of peripheral bone growth was measured (bounded by yellow). Images were generated by ImagePro Premier software, version 9.3 (Media Cybernetics, https://www.mediacy.com/imageproplus).