Table 2 Hazard ratios (and 95% CI values) of cardiovascular disease risk during a median 13.3 years of follow-up according to baseline lipid profiles in TwSHHH 2002.

From: Association of baseline as well as change in lipid levels with the risk of cardiovascular diseases and all-cause deaths

 

1

2

3

4

Trend test

Total cholesterol

Events

24

49

61

91

 

Person-years

12,541

14,046

13,632

13,716

 

Incidence rate

1.9

3.5

4.5

6.6

 

Model1

1

1.66(0.94–2.91)

1.80(1.03–3.14)

2.67(1.58–4.50)

 < .0001

Model2

1

1.57(0.89–2.75)

1.53(0.87–2.67)

2.13(1.26–3.62)

0.004

Model3

1

1.45(0.83–2.55)

1.49(0.86–2.58)

1.70(1.00–2.89)

0.07

Triglycerides

Events

23

38

70

91

 

Person-years

12,870

13,220

13,882

13,607

 

Incidence rate

1.8

2.9

5

6.7

 

Model1

1

1.19(0.66–2.17)

1.96(1.14–3.37)

2.4(1.41–4.08)

0.000

Model2

1

1.08(0.59–1.97)

1.59(0.92–2.77)

1.82(1.05–3.17)

0.010

Model3

1

0.94(0.53–1.69)

1.27(0.74–2.17)

1.21(0.70–2.10)

0.36

LDL cholesterol

Events

23

46

72

84

 

Person-years

12,369

14,065

14,143

13,358

 

Incidence rate

1.9

3.3

5.1

6.3

 

Model1

1

1.33(0.75–2.36)

1.95(1.15–3.30)

2.16(1.29–3.64)

0.001

Model2

1

1.25(0.70–2.21)

1.60(0.94–2.72)

1.72(1.02–2.91)

0.029

Model3

1

1.34(0.76–2.38)

1.33(0.77–2.30)

1.51(0.89–2.59)

0.16

NonHDL cholesterol

Events

20

43

68

94

 

Person-years

12,393

13,708

14,339

13,495

 

Incidence rate

1.6

3.1

4.7

7.0

 

Model1

1

1.78(0.97–3.27)

2.25(1.26–4.01)

2.79(1.58–4.92)

0.000

Model2

1

1.58(0.86–2.91)

1.76(0.98–3.16)

2.08(1.17–3.69)

0.015

Model3

1

1.62(0.87–3.02)

1.51(0.83–2.77)

1.70(0.94–3.09)

0.17

Apolipoprotein B

Events

16

41

70

98

 

Person–years

12,058

14,040

13,994

13,801

 

Incidence rate

1.3

2.9

5.0

7.1

 

Model1

1

2.85(1.37–5.94)

2.97(1.44–6.13)

5.03(2.50–10.13)

 < .0001

Model2

1

2.44(1.17–5.10)

2.27(1.09–4.71)

3.48(1.70–7.11)

0.001

Model3

1

1.80(0.89–3.64)

1.76(0.88–3.53)

2.05(1.03–4.08)

0.08

  1. Incidence rates are presented per 1000 person-years; Model 1: adjusted for age groups (20–64/ ≥ 65 years old) and sex. Model 2: as for model 1 plus body mass index (18.4/18.5–23.9/24.0–26.9/ ≥ 27 kg/m2), current smoker (yes/no), alcohol drinking (yes/no), marital status (single, divorced or separated/Living with spouse), regular exercise habit (yes/no),education level (9 years/at least 9 years), income level (monthly income level < 40,000, ≥ 40,000 New Taiwan Dollars). Model 3: as for model 2 plus baseline hypertension (yes/no), diabetes mellitus (yes/no), menopause(yes/no), family history of CVD (yes/no), and hsCRP level.
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