Table 1 Clinical-epidemiological features of the GWTS, qRT-PCR and ISH assay cohorts.
GWTS cases (n = 4) | GWTS controls (n = 3) | p-value | qRT-PCR cases (n = 10) | qRT-PCR controls (n = 8) | p-value | ISH cases (n = 9) | ISH controls (n = 8) | p-value | |
|---|---|---|---|---|---|---|---|---|---|
Age (mean ± SD, years) | 52 ± 15 | 58 ± 16 | 0.21 | 49 ± 15 | 42 ± 10 | 0.31 | 45 ± 11 | 44 ± 7 | 0.63 |
Female | 75% (3/4) | 67% (2/3) | 1 | 50% (5/10) | 50% (4/8) | 1 | 56% (5/9) | 38% (3/8) | 0.64 |
Smoker | 25% (1/4) | 33% (1/3) | 1 | 10% (1/10) | 25% (2/8) | 0.56 | 11% (1/9) | 50% (4/8) | 0.13 |
HTN | 0% | 33% (1/3) | 0.43 | 36% (3/10) | 13% (1/8) | 0.59 | 22% (2/9) | 13% (1/8) | 1 |
DM | 0% | 0% | 1 | 10% (1/10) | 0% | 1 | 0% | 0% | 1 |
Dyslipidemia | 25% (1/4) | 0% | 1 | 30% (3/10) | 25% (2/8) | 1 | 22% (2/9) | 25% (2/8) | 1 |
Migraine | 50% (2/4) | 67% (2/3) | 1 | 30% (3/10) | 25% (2/8) | 0.19 | 56% (5/9) | 29% (2/7) | 0.36 |
Psychiatric disease | 25% (1/4) | 33% (1/3) | 1 | 60% (6/10) | 25% (2/8) | 0.61 | 66% (6/9) | 38% (3/8) | 0.35 |
Stroke | 0% | 0% | 1 | 40% (4/10) | 0% | 0.25 | 33% (3/9) | 0% | 0.21 |
Dementia | 0% | 0% | 1 | 0% | 0% | 1 | 0% | 0% | 1 |
