Table 1 Demographic and clinical information of the study subjects.
Clinical variables | Discovery stage (N = 3306) | Statistics | P value | Replication stage (N = 2530) | Statistics | P value | ||
|---|---|---|---|---|---|---|---|---|
Cases (N = 1042) | Controls (N = 2264) | Cases (N = 842) | Controls (N = 1688) | |||||
Age, mean ± SD | 37.8 ± 7.2 | 37.8 ± 7.4 | t = 0.14 | 0.89 | 36.7 ± 7.1 | 36.8 ± 7.0 | t = −0.34 | 0.73 |
Gender (%) | ||||||||
Male | 295 (28) | 643 (28) | 187 (22) | 1310 (78) | ||||
Female | 747 (72) | 1621 (72) | χ2 = 0.0001 | 0.99 | 655 (78) | 378 (22) | χ2 = 0.0029 | 0.96 |
Family history (%) | ||||||||
Yes | 68 (7) | 120 (5) | 62 (7) | 105 (4) | ||||
No | 974 (93) | 2144 (95) | χ2 = 1.78 | 0.18 | 780 (93) | 1583 (96) | χ2 = 1.01 | 0.31 |
Unilateral pain (%) | ||||||||
Yes | 792 (76) | – | 690 (82) | – | ||||
No | 250 (24) | – | – | – | 152 (18) | – | – | – |
Pulsating pain (%) | ||||||||
Yes | 677 (65) | – | 581 (69) | – | ||||
No | 365 (35) | – | – | – | 261 (31) | – | – | – |
Nausea (%) | ||||||||
Yes | 854 (82) | – | 674 (80) | – | ||||
No | 188 (18) | – | – | – | 168 (20) | – | – | – |
Vomiting (%) | ||||||||
Yes | 771 (74) | – | 598 (71) | – | ||||
No | 271 (26) | – | – | – | 244 (29) | – | – | – |
Photophobia (%) | ||||||||
Yes | 834 (80) | – | 657 (78) | – | ||||
No | 208 (20) | – | – | – | 185 (22) | – | – | – |
Phonophobia (%) | ||||||||
Yes | 896 (86) | – | 699 (83) | – | ||||
No | 146 (14) | – | – | – | 143 (17) | – | – | – |
Aggrevation by physical activity (%) | ||||||||
Yes | 969 (93) | – | 758 (90) | – | ||||
No | 73 (7) | – | – | – | 84 (10) | – | – | – |
