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Figure 2

From: Glutathione ethyl ester reverses the deleterious effects of fentanyl on ventilation and arterial blood-gas chemistry while prolonging fentanyl-induced analgesia

Figure 2

Effects of fentanyl (75 μg/kg, IV) on arterial blood pH, pO2, pCO2 and sO2 values and Alveolar-arterial (A-a) gradients in rats pretreated with vehicle (VEH; 1 ml/kg, IV) or GSHee (100 μmol/kg, IV). The data are presented as mean ± SEM. The data were analyzed by repeated measures ANOVA followed by multiple comparison testing as detailed in the Methods section. There were 9 rats in each group. *P < 0.05/5 comparisons per group, significant change from post-drug. †P < 0.05/5 between group comparisons, GSHee versus vehicle.

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