Figure 8 | Scientific Reports

Figure 8

From: CRISPR/Cas9 generated knockout mice lacking phenylalanine hydroxylase protein as a novel preclinical model for human phenylketonuria

Figure 8

Nest building assay for behavioral competence. (A) Nesting behavior was assessed in the home cages using packed cotton material. The mice first shred the tightly packed material, then arrange it into a nest overnight. Semiquantiative score, shown above the images, is assigned based on the quality of the nest. (B) Scatter plot graphs show individual animal nesting score. n = 7 Hom, 7 Het. Group columns represent median scores and the error bars indicate range in Hom and Het mice at various timepoints (***p = 0.0006).

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