Table 2 Variance polygenic score (vPGS) validation in the UK Biobank.

From: The impact of late-career job loss and genetic risk on body mass index: Evidence from variance polygenic scores

 

Model 1

Model 2

vPGS

Beta (SE)

Beta (SE)

95% CI

95% CI

p value

p value

0.019 (0.005)

0.019 (0.005)

[0.009, 0.029]

[0.009, 0.029]

1.01E−04

1.44E−04

  1. Abbreviations: SE, standard error; CI, confidence interval. Results show the association between the vPGS and the between-individual variance in BMI in a 20% holdout sample of the UK Biobank. Model 2 adjusts for the effect of the mean PGS (mPGS). Unique N = 81,375.