Figure 7

Schematic diagram of convex hull analysis of CAV1 WT and CSD mutant scaffold blobs. Increased variance of the convex hull boundary at high shrink factors (most indented) compared to low shrink factors (the most convex) is suggestive of the more variable distribution of N-terminal CAV1 labeling in CAV1 WT relative to CAV1 CSD mutant scaffold domains. CSD indicated by blue box and N-terminus of CAV1 by N. Membrane is in green and convex hull boundary of CAV1 point clouds at shrink factor 1 in blue and at shrink factor 0 in red. Representative CAV1 domains are shown containing 6 CAV1′s and do not correspond in size, number or scale to any known CAV1 scaffold. Adapted from³⁹.