Table 1 Nerve infiltration in the pancreatic tumor microenvironment and its correlation with clinicopathological variables.
From: Tumor innervation and clinical outcome in pancreatic cancer
Parameters | Nerve negative | Nerve positive | Undefined | p-value |
|---|---|---|---|---|
Pathology description | N (%) | |||
Normal (n = 71) | 20 (28) | 3 (13) | 48 (68) | 0.74 |
Cancer (n = 99) | 47 (47) | 10 (10) | 42 (42) | |
Cancer histological subtype | ||||
Ductal adenocarcinoma (n = 88) | 40 (45) | 10 (11) | 38 (43) | 0.33 |
Others (n = 11) | 7 (64) | 0 (0) | 4 (36) | |
Sex | ||||
Male (n = 63) | 26 (41) | 5 (8) | 32 (51) | 1.0 |
Female (n = 36) | 21 (58) | 5 (14) | 10 (28) | |
Age (years) | ||||
≤ 50 (n = 16) | 8 (50) | 3 (19) | 5 (31) | 0.38 |
> 50 (n = 83) | 39 (47) | 7 (8) | 37 (45) | |
Tumor grade | ||||
G1 (n = 11) | 4 (36) | 3 (27) | 4 (36) | 0.09 |
G2 + G3 (n = 88) | 43 (49) | 7 (8) | 38 (43) | |
Tumor stage | ||||
0 + I (n = 40) | 19 (47) | 4 (10) | 17 (42) | 1.0 |
II + IV (n = 59) | 28 (47) | 6 (10) | 25 (42) | |
Tumor size | ||||
T1 + T2 (n = 78) | 37 (47) | 8 (10) | 33 (42) | 1.0 |
T3 (n = 20) | 10 (50) | 2 (10) | 8 (40) | |
Lymphatic metastasis status | ||||
Negative (n = 50) | 25 (50) | 4 (8) | 21 (42) | 0.45 |
Positive (n = 43) | 18 (42) | 5 (12) | 20 (46) | |
Survival status (months) | ||||
Survival > 10 months (n = 49) | 26 (53) | 3 (6) | 20 (41) | 0.17 |
Survival ≤ 10 months (n = 50) | 21 (42) | 7 (14) | 22 (44) | |
