Figure 1

Plasma cytokine levels differ between responders (labelled S loss) and non-responders (labelled No S loss) during peg-IFN-α therapy. (A) Trend of quantitative HBsAg (qHBsAg) levels between the responders (S loss) and non-responders (non S loss) in the cohort combined from the Add-on and Switch arms. The numbers below indicate the median value of the qHBsAg for each group at the time-points indicated. (B) Heat map of cytokine levels from the plasma samples analysed at the three time-points indicated. The heat map data was clustered on the cytokines and chemokines and separated by time-points. Heat map shows data from responders (S loss; n = 14) and non-responders (No S loss; n = 12). Scale bar indicates the Z score of the normalised cytokine and chemokine values (red, high; green, low).