Figure 2 | Scientific Reports

Figure 2

From: Identification of potential therapeutic antimicrobial peptides against Acinetobacter baumannii in a mouse model of pneumonia

Figure 2

Peritoneal administration of TP4 derivatives in A. baumannii-induced pneumonia mouse models. (A) Mice were intratracheally infected with A. baumannii ATCC 17,978 at a dose of 5 × 108 CFU. TP4 derivatives (2 mg/kg) were peritoneally administrated 4 h after bacterial infection, and mouse survival was detected daily (n = 5/group). (B) A. baumannii ATCC 17,978 (2–5 × 105 CFU) were mixed with 1 × and 2 × MIC of dN4 (32 and 64 μg/mL) or dC4 (32 and 64 μg/mL), and incubated at 37 °C. The survival bacteria were detected by plating on agar plate.

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