Figure 4 | Scientific Reports

Figure 4

From: A method to analyze the influence of mechanical strain on dermal collagen morphologies

Figure 4

FINE algorithm parameters of the collagen fiber families of the isotropic and the anisotropic sample under repeated stretching and relaxation. (a) Averaged force acting on the isotropic sample, measured by the force sensors as a function of the deformation cycle number. (b) Dispersion parameter b of each fiber family identified by the FINE algorithm in the isotropic sample as a function of the deformation cycle number. Data points with error bars indicating the \(95\,\%\) confidence intervals are shown in grey. Solid lines represent smoothed data points. Note that, a third fiber family is identified in a negligible fraction of images (\(\le 1\,\%\)). For the sake of clarity, parameters of this fiber family are not shown. The line at \(b=0.05\) indicates the threshold value below which a fiber family is considered as isotropic. (c) Amplitude of each fiber family identified by the FINE algorithm in the isotropic sample as a function of the deformation cycle number. (d) Averaged force acting on the anisotropic sample, measured by the force sensors as a function of the deformation cycle number. (e) Dispersion parameter b of each fiber family identified by the FINE algorithm in the anisotropic sample as a function of the deformation cycle number. (f) Amplitude of each fiber family identified by the FINE algorithm in the anisotropic sample as a function of the deformation cycle number.

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