Table 2 Number of hospitalizations, hospital length of stay, in-hospital mortality, and charges for the top 10 complications of systemic therapy, 2005–2016 (n = 2,419,722).

From: Hospitalization rates for complications due to systemic therapy in the United States

Diagnosis

Number of hospitalizations (%, 95% CI)

Length of stay in days, median (IQR)

Mortality, % (95% CI)

Median Charges per Hospitalization (95% CI)

Total Charges in Billions (95% CI)

Anemia

309,724 (12.8%, 9.7–13.1%)

4.9 (2.4–14.6)

2.8% (2.6–3.4%)

$12,024 ($11,373–$12,674)

$4.62 ($4.11–$5.12)

Neutropenia

261,330 (10.8%, 7.9–11.0%)

3.9 (2.3–6.5)

1.6% (1.4–2.8%)

$9091 ($8804–$9377)

$2.49 ($2.24–$2.74)

Sepsis

188,738 (7.8%, 6.0–8.1%)

6.1 (3.4–11.5)

15.8% (15.4–17.9%)

$16,834 ($16,361–$17,307)

$3.01 ($2.78–$3.22)

Pneumonia

106,468 (4.4%, 3.4–4.8%)

5.5 (3.1–10.4)

7.6% (7.1–10.6%)

$13,040 ($12,541–$13,538)

$1.65 ($1.49–$1.82)

Acute kidney injury

87,110 (3.6%, 2.8–3.7%)

5.2 (2.8–10.2)

7.0% (6.6–10.2%)

$13,172 ($12,381–$13,963)

$1.34 ($1.17–$1.51)

Nausea with vomiting

77,431 (3.2%, 2.3–3.3%)

2.6 (1.4–4.4)

0.70% (0.55–1.1%)

$6059 ($5856–$6261)

$0.43 ($0.40–$0.47)

Dehydration

72,592 (3.0%, 2.0–3.4%)

3.0 (1.6–5.5)

2.8% (2.5–3.6%)

$6351 ($6159–$6543)

$0.51 ($0.47–$0.55)

Urinary tract infection

31,459 (1.3%, 0.93–1.4%)

3.6 (2.1–6.2)

1.5% (1.1–4.4%)

$8460 ($8135–$8784)

$0.29 ($0.26–$0.32)

Congestive heart failure

31,456 (1.3%, 0.87–1.5%)

4.0 (2.3–7.1)

4.1% (3.6–5.1%)

$10,120 ($9701–$10,537)

$0.32 ($0.29–$0.35)

Fever of unknown origin

26,617 (1.1%, 0.71–1.2%)

2.4 (1.4–4.2)

0.33% (0.18–1.1%)

$6236 ($5920–$6552)

$0.18 ($0.15–$0.21)