Table 2 Number of hospitalizations, hospital length of stay, in-hospital mortality, and charges for the top 10 complications of systemic therapy, 2005–2016 (n = 2,419,722).
From: Hospitalization rates for complications due to systemic therapy in the United States
Diagnosis | Number of hospitalizations (%, 95% CI) | Length of stay in days, median (IQR) | Mortality, % (95% CI) | Median Charges per Hospitalization (95% CI) | Total Charges in Billions (95% CI) |
|---|---|---|---|---|---|
Anemia | 309,724 (12.8%, 9.7–13.1%) | 4.9 (2.4–14.6) | 2.8% (2.6–3.4%) | $12,024 ($11,373–$12,674) | $4.62 ($4.11–$5.12) |
Neutropenia | 261,330 (10.8%, 7.9–11.0%) | 3.9 (2.3–6.5) | 1.6% (1.4–2.8%) | $9091 ($8804–$9377) | $2.49 ($2.24–$2.74) |
Sepsis | 188,738 (7.8%, 6.0–8.1%) | 6.1 (3.4–11.5) | 15.8% (15.4–17.9%) | $16,834 ($16,361–$17,307) | $3.01 ($2.78–$3.22) |
Pneumonia | 106,468 (4.4%, 3.4–4.8%) | 5.5 (3.1–10.4) | 7.6% (7.1–10.6%) | $13,040 ($12,541–$13,538) | $1.65 ($1.49–$1.82) |
Acute kidney injury | 87,110 (3.6%, 2.8–3.7%) | 5.2 (2.8–10.2) | 7.0% (6.6–10.2%) | $13,172 ($12,381–$13,963) | $1.34 ($1.17–$1.51) |
Nausea with vomiting | 77,431 (3.2%, 2.3–3.3%) | 2.6 (1.4–4.4) | 0.70% (0.55–1.1%) | $6059 ($5856–$6261) | $0.43 ($0.40–$0.47) |
Dehydration | 72,592 (3.0%, 2.0–3.4%) | 3.0 (1.6–5.5) | 2.8% (2.5–3.6%) | $6351 ($6159–$6543) | $0.51 ($0.47–$0.55) |
Urinary tract infection | 31,459 (1.3%, 0.93–1.4%) | 3.6 (2.1–6.2) | 1.5% (1.1–4.4%) | $8460 ($8135–$8784) | $0.29 ($0.26–$0.32) |
Congestive heart failure | 31,456 (1.3%, 0.87–1.5%) | 4.0 (2.3–7.1) | 4.1% (3.6–5.1%) | $10,120 ($9701–$10,537) | $0.32 ($0.29–$0.35) |
Fever of unknown origin | 26,617 (1.1%, 0.71–1.2%) | 2.4 (1.4–4.2) | 0.33% (0.18–1.1%) | $6236 ($5920–$6552) | $0.18 ($0.15–$0.21) |