Figure 3
Milk EVs restore villus architecture in malnourished mice. Analysis of intestinal morphology of: controls, i.e., sham-treated mice fed 18% protein diet; sham-treated mice fed 1% protein diet; and milk EV-treated mice fed 1% protein diet: (a) H&E stained sections of jejunum and associated measurements of (b) Villus height and crypt depth, n = 7/group. (c) H&E stained sections of ileum and associated measurements of (d) Villus height and crypt depth, n = 7/group. Each column represents mean ± standard error of mean (SEM). (****P < 0.0001, **P < 0.01, *P < 0.05, n.s = not significant), scale bar 50 nm. Graphs and statistical tests were done using GraphPad Prism version 6.0.0 for Windows (www.graphpad.com).
