Table 3 Association of serum Na decrease (mmol/L) and pre-HD ECW/TBW (%) with SBP decrease index (%) in mixed linear regression.

From: Serum sodium variation is a major determinant of peridialytic blood pressure trends in haemodialysis outpatients

 

Serum Na decreasea (mmol/L)

Pre-HD ECW/TBWa (%)

β (95% CI)

P value

β (95% CI)

P value

Univariate

1.18 (0.30 to 2.05)

0.008

− 1.31 (− 2.23 to − 0.39)

0.005

Model 1

1.07 (0.18 to 1.95)

0.017

− 1.05 (− 2.12 to 0.01)

0.053

Model 2

0.98 (0.11 to 1.86)

0.027

− 0.62 (− 1.73 to 0.49)

0.276

Model 3

1.24 (0.37 to 2.11)

0.005

− 0.85 (− 1.96 to 0.25)

0.133

  1. Model 1 is adjusted for: K decrease, urea decrease, pre-HD glucose, age, square of age, gender, ethnicity, BMI, diabetes, antihypertensive medication, coronary artery disease and congestive heart failure.
  2. Model 2 is adjusted for same variables as model 1 as well as: serum albumin, presence of AVF and dialysis vintage.
  3. Model 3 is adjusted for same variables as model 2 as well as: dialysate calcium, dialysate temperature, UFR, session time and Kt/V.
  4. Na sodium, HD haemodialysis, ECW extracellular water, TBW total body water, SBP systolic blood pressure, K potassium, BMI body mass index, AVF arteriovenous fistula, UFR ultrafiltration rate.
  5. aStandardized to a mean of 0 and a SD of 1.
  6. Bold values correspond to p < 0.05.